Micky van de Ven Brace Ends The Toffees' Run at Brand New Home Ground
Micky van de Ven became the first backline player to net twice in a English top-flight match for Tottenham since Jan Vertonghen in spring 2013.
Match summary
The Spurs defender heads into the net two times in opening period
The home side's Jake O'Brien has equalizer ruled after VAR review
Senegalese midfielder nets third in dying moments
The defeat is the Merseyside club's initial at Hill Dickinson Stadium
The Tottenham defender scored on two occasions as Tottenham extended their winning streak in away games in the Premier League and handed the Toffees their initial loss at Hill Dickinson Stadium.
Everton were undefeated in their last five matches at their recently opened stadium at the dockside location, having left Goodison Park behind after more than a century at the conclusion of last season.
But Tottenham's leader Van de Ven struck twice from corners in the opening 45 minutes to place their strong form at jeopardy, and they were failed to mount a comeback before the midfielder - assisted by ex-Everton forward the Brazilian - headed home a third to put the game to bed.
The Everton defender thought he had equalized the tally a short while after Van de Ven's opener, glancing a bullet header past the Spurs keeper from an Everton corner.
The Portuguese striker, in the meantime, failed to convert a handful of chances, while the Italian goalkeeper made a series of excellent stops to ensure the London club went five away games without defeat in the Premier League.
But the video assistant referee intervened, advising Craig Pawson to review the score on the pitchside monitor and the referee decided that the winger and the attacker were in an illegal position and had interfered with the Spurs keeper.
This victory moves the manager's team up to third in the division, a handful of points off local foes and leaders Arsenal.
The Merseyside club stay in 14th position and sit six points clear of the relegation zone.
Tottenham analysis: Van de Ven fulfils duties at each end of the field
After a drab midweek display in the Champions League against Monaco, where they managed a only two shots on goal, Frank opted for the French striker in attack instead of ex-Everton forward the Brazilian.
The summer signing was failed to influence the game before being substituted for the substitute after an hour on the field, but it turns out he wasn't needed in the final outcome.
Defender Van de Ven transformed into an offensive threat to be feared.
Tottenham's opening strike came from a well-worked corner routine, with the midfielder heading the ball toward the face of goal for an free the defender to score.
And Ven de Ven - stepping up as captain in Cristian Romero's absence - added his second in added time as he rose above the England keeper to head home.
The Dutchman was just as impressive in defensive duties, combining effectively with Kevin Danso as the duo dealt excellently with the 34 crosses thrown their way by the opposition.
Everton analysis: Toffees lacking finishing touch
The club's new home had been a fortress, but it seems the novelty may have worn off slightly and supporters headed to the gates after the midfielder's third for Spurs.
The end in Everton's unbeaten home run won't be a massive worry for David Moyes, but their striker situation will be.
The forward and Thierno Barry - the Everton's pair of recognised centre-forwards - had netted only one league goal between them before the weekend's match.
And they were unable to add to that miserable tally on a wet and gloomy evening on Merseyside.
The striker's performance was summed up when he opted to bicycle-kick a clear chance from near the goal, despite having space and opportunity to reposition for a simpler shot that would have tested the keeper.
Barry, as well, failed to influence the game after replacing Beto in the second half.
It was not for a shortage of chance. The majority of the home side's offensive moves came through Grealish and the forward, who relentlessly whipped threatening crosses into the Spurs penalty area.
What next for both teams?
Everton: Moyes' men travel to Sunderland in the Premier League on early November at 20:00 GMT.
Tottenham: The London club go to Newcastle's ground on late October for their fourth-round League Cup match against Newcastle.